Prognostic value of TP53 expression and MGMT methylation in glioblastoma patients treated with temozolomide combined with other chemotherapies

OBJECTIVE: To assess the recurrence interval and predictive significance of TP53 expression and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in glioblastomas treated with radiotherapy and combined chemotherapies, including temozolomide, lomustine, procarbazine and bevacizumab....

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Kurdi, Maher, Butt, Nadeem Shafique, Baeesa, Saleh, Alghamdi, Badrah, Maghrabi, Yazid, Bardeesi, Anas, Saeedi, Rothaina, Dallol, Ashraf, Mohamed, Fawaz, Bari, Mohammed O., Samkari, Alaa, Lary, Ahmed I., Alkhayyat, Shadi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084807/
https://ncbi.nlm.nih.gov/pubmed/33661424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-021-03723-9
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