The Impact of Differentiation on Cytotoxicity and Insulin Sensitivity in Streptozotocin Treated SH-SY5Y Cells

Recently neuronal insulin resistance was suggested playing a role in Alzheimer’s disease. Streptozotocin (STZ) is commonly used to induce impairment in insulin metabolism. In our previous work on undifferentiated SH-SY5Y cells the compound exerted cytotoxicity without altering insulin sensitivity. N...

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Bibliografiske detaljer
Udgivet i:Neurochem Res
Main Authors: Bagaméry, Fruzsina, Varga, Kamilla, Kecsmár, Kitti, Vincze, István, Szökő, Éva, Tábi, Tamás
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2021
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084777/
https://ncbi.nlm.nih.gov/pubmed/33616807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-021-03269-2
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