Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface

BACKGROUND: Pregnant women are at increased risk for severe outcomes from coronavirus disease 2019 (COVID-19), but the pathophysiology underlying this increased morbidity and its potential effect on the developing fetus is not well understood. METHODS: We assessed placental histology, ACE2 expressio...

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Detalhes bibliográficos
Publicado no:Med (N Y)
Main Authors: Lu-Culligan, Alice, Chavan, Arun R., Vijayakumar, Pavithra, Irshaid, Lina, Courchaine, Edward M., Milano, Kristin M., Tang, Zhonghua, Pope, Scott D., Song, Eric, Vogels, Chantal B.F., Lu-Culligan, William J., Campbell, Katherine H., Casanovas-Massana, Arnau, Bermejo, Santos, Toothaker, Jessica M., Lee, Hannah J., Liu, Feimei, Schulz, Wade, Fournier, John, Muenker, M. Catherine, Moore, Adam J., Konnikova, Liza, Neugebauer, Karla M., Ring, Aaron, Grubaugh, Nathan D., Ko, Albert I., Morotti, Raffaella, Guller, Seth, Kliman, Harvey J., Iwasaki, Akiko, Farhadian, Shelli F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2021
Assuntos:
Clinical and Translational Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084634/
https://ncbi.nlm.nih.gov/pubmed/33969332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medj.2021.04.016
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