CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury

Zebrafish exhibit robust regeneration following spinal cord injury, promoted by macrophages that control post-injury inflammation. However, the mechanistic basis of how macrophages regulate regeneration is poorly understood. To address this gap in understanding, we conducted a rapid in vivo phenotyp...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Keatinge, Marcus, Tsarouchas, Themistoklis M., Munir, Tahimina, Porter, Nicola J., Larraz, Juan, Gianni, Davide, Tsai, Hui-Hsin, Becker, Catherina G., Lyons, David A., Becker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084196/
https://ncbi.nlm.nih.gov/pubmed/33914736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009515
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