Rapid Assessment of Hyperdiploidy in Plasma Cell Disorders Using a Novel Multi-Parametric Flow Cytometry Method

Trisomies of odd numbered chromosomes are seen in nearly half of patients with multiple myeloma (MM) and typically correlate with a hyperdiploid state and better overall survival (OS). We compared DNA ploidy of monoclonal plasma cells (as a surrogate for the presence of trisomies) assessed simultane...

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Vydáno v:Am J Hematol
Hlavní autoři: Sidana, Surbhi, Jevremovic, Dragan, Ketterling, Rhett P., Tandon, Nidhi, Dispenzieri, Angela, Gertz, Morie A., Greipp, Patricia T, Baughn, Linda B., Buadi, Francis K., Lacy, Martha Q., Morice, William, Hanson, Curtis, Timm, Michael, Dingli, David, Hayman, Suzanne R., Gonsalves, Wilson I., Kapoor, Prashant, Kyle, Robert A., Leung, Nelson, Go, Ronald S., Lust, John A., Rajkumar, S.Vincent, Kumar, Shaji K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083940/
https://ncbi.nlm.nih.gov/pubmed/30592078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25391
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