Rapid Assessment of Hyperdiploidy in Plasma Cell Disorders Using a Novel Multi-Parametric Flow Cytometry Method

Trisomies of odd numbered chromosomes are seen in nearly half of patients with multiple myeloma (MM) and typically correlate with a hyperdiploid state and better overall survival (OS). We compared DNA ploidy of monoclonal plasma cells (as a surrogate for the presence of trisomies) assessed simultane...

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izdano v:Am J Hematol
Main Authors: Sidana, Surbhi, Jevremovic, Dragan, Ketterling, Rhett P., Tandon, Nidhi, Dispenzieri, Angela, Gertz, Morie A., Greipp, Patricia T, Baughn, Linda B., Buadi, Francis K., Lacy, Martha Q., Morice, William, Hanson, Curtis, Timm, Michael, Dingli, David, Hayman, Suzanne R., Gonsalves, Wilson I., Kapoor, Prashant, Kyle, Robert A., Leung, Nelson, Go, Ronald S., Lust, John A., Rajkumar, S.Vincent, Kumar, Shaji K.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083940/
https://ncbi.nlm.nih.gov/pubmed/30592078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25391
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