Broad SARS-CoV-2 cell tropism and immunopathology in lung tissues from fatal COVID-19

BACKGROUND: COVID-19 patients manifest with pulmonary symptoms reflected by diffuse alveolar damage (DAD), excessive inflammation, and thromboembolism. The mechanisms mediating these processes remain unclear. METHODS: We performed multicolor staining for SARS-CoV-2 proteins and lineage markers to de...

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Vydáno v:J Infect Dis
Hlavní autoři: Ramos da Silva, Suzane, Ju, Enguo, Meng, Wen, Paniz Mondolfi, Alberto E, Dacic, Sanja, Green, Anthony, Bryce, Clare, Grimes, Zachary, Fowkes, Mary, Sordillo, Emilia M, Cordon-Cardo, Carlos, Guo, Haitao, Gao, Shou-Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Major Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083355/
https://ncbi.nlm.nih.gov/pubmed/33837392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiab195
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