In Silico Evaluation of Cyclophilin Inhibitors as Potential Treatment for SARS-CoV-2

BACKGROUND: The advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provoked researchers to propose multiple antiviral strategies to improve patients’ outcomes. Studies provide evidence that cyclosporine A (CsA) decreases SARS-CoV-2 replication in vitro and decreases mortality rat...

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Foilsithe in:Open Forum Infect Dis
Main Authors: Laurie, Kyle, Holcomb, David, Kames, Jacob, Komar, Anton A, DiCuccio, Michael, Ibla, Juan C, Kimchi-Sarfaty, Chava
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2021
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Major Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083350/
https://ncbi.nlm.nih.gov/pubmed/34109257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofab189
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