Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis

BACKGROUND: Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by progressive surfactant accumulation and hypoxemia caused by disruption of signaling by granulocyte/macrophage-colony stimulating factor (GM-CSF), which pulmonary alveolar macrophages require to clear surf...

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Publicado no:N Engl J Med
Main Authors: Trapnell, Bruce C., Inoue, Yoshikazu, Bonella, Francesco, Morgan, Cliff, Jouneau, Stéphane, Bendstrup, Elisabeth, Campo, Ilaria, Papiris, Spyros A., Yamaguchi, Etsuro, Cetinkaya, Erdogan, Ilkovich, Mikhail M., Kramer, Mordechai R., Veltkamp, Marcel, Kreuter, Michael, Baba, Tomohisa, Ganslandt, Cecilia, Tarnow, Inge, Waterer, Grant, Jouhikainen, Taneli
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083051/
https://ncbi.nlm.nih.gov/pubmed/32897035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1913590
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