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The emerging role of β-secretases in cancer

BACE1 and BACE2 belong to a class of proteases called β-secretases involved in ectodomain shedding of different transmembrane substrates. These enzymes have been extensively studied in Alzheimer's disease as they are responsible for the processing of APP in neurotoxic Aβ peptides. These proteas...

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Bibliografski detalji
Izdano u:J Exp Clin Cancer Res
Glavni autori: Farris, Francesco, Matafora, Vittoria, Bachi, Angela
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082908/
https://ncbi.nlm.nih.gov/pubmed/33926496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01953-3
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