Reduced pericyte and tight junction coverage in old diabetic rats are associated with hyperglycemia-induced cerebrovascular pericyte dysfunction

Diabetes mellitus (DM) is one of the primary pathological factors that contributes to aging-related cognitive impairments, but the underlying mechanisms remain unclear. We recently reported that old DM rats exhibited impaired myogenic responses of the cerebral arteries and arterioles, poor cerebral...

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Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Liu, Yedan, Zhang, Huawei, Wang, Shaoxun, Guo, Ya, Fang, Xing, Zheng, Baoying, Gao, Wenjun, Yu, Hongwei, Chen, Zongbo, Roman, Richard J., Fan, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082790/
https://ncbi.nlm.nih.gov/pubmed/33306445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00726.2020
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