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Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment

BACKGROUND: Whole-genome sequencing has shown that the Mycobacterium tuberculosis infection process can be more heterogeneous than previously thought. Compartmentalized infections, exogenous reinfections, and microevolution are manifestations of this clonal complexity. The analysis of the mechanisms...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Fernandez Do Porto, Darío A., Monteserin, Johana, Campos, Josefina, Sosa, Ezequiel J., Matteo, Mario, Serral, Federico, Yokobori, Noemí, Benevento, Andrés Fernández, Poklepovich, Tomás, Pardo, Agustín, Wainmayer, Ingrid, Simboli, Norberto, Castello, Florencia, Paul, Roxana, Martí, Marcelo, López, Beatriz, Turjanski, Adrián, Ritacco, Viviana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082761/
https://ncbi.nlm.nih.gov/pubmed/33926375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-021-06069-9
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