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A non-convulsant delta opioid receptor agonist, KNT-127, reduces cortical spreading depression and nitroglycerin-induced allodynia

OBJECTIVE: The aim of this study was to determine if the non-convulsant delta opioid receptor agonist, KNT-127, could inhibit migraine-associated endpoints. BACKGROUND: The delta opioid receptor has been identified as a therapeutic target for migraine. However, development of delta agonists is limit...

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Detalhes bibliográficos
Publicado no:Headache
Main Authors: Bertels, Zachariah, Witkowski, Wiktor D, Asif, Sarah, Siegersma, Kendra, van Rijn, Richard M, Pradhan, Amynah A
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082730/
https://ncbi.nlm.nih.gov/pubmed/33326598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/head.14019
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