TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/−ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential

BACKGROUND: Tumor necrosis factor-α (TNF-α) is an immunostimulatory cytokine that is consistently high in the breast tumor microenvironment (TME); however, its differential role in mitochondrial functions and cell survival in ER/PR +ve and ER/PR −ve breast cancer cells is not well understood. METHOD...

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Bibliografiske detaljer
Udgivet i:Cancer Metab
Main Authors: Shinde, Anjali, Jung, Hyeryeon, Lee, Hayun, Singh, Kritarth, Roy, Milton, Gohel, Dhruv, Kim, Han Byeol, Mane, Minal, Vasiyani, Hitesh, Currim, Fatema, Seo, Yu Ri, Yang, Seojin, Cho, Ara, Yi, Eugene C., Singh, Rajesh
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082668/
https://ncbi.nlm.nih.gov/pubmed/33926547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00254-9
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