N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies

The N6-methyladenosine (m6A) modification is a dynamic and reversible epigenetic modification, which is co-transcriptionally deposited by a methyltransferase complex, removed by a demethylase, and recognized by reader proteins. Mechanistically, m6A modification regulates the expression levels of mRN...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Tan, Fenghua, Zhao, Mengyao, Xiong, Fang, Wang, Yumin, Zhang, Shanshan, Gong, Zhaojian, Li, Xiayu, He, Yi, Shi, Lei, Wang, Fuyan, Xiang, Bo, Zhou, Ming, Li, Xiaoling, Li, Yong, Li, Guiyuan, Zeng, Zhaoyang, Xiong, Wei, Guo, Can
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082653/
https://ncbi.nlm.nih.gov/pubmed/33926508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01952-4
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