PHLDA3 inhibition attenuates endoplasmic reticulum stress-induced apoptosis in myocardial hypoxia/reoxygenation injury by activating the PI3K/AKT signaling pathway

Endoplasmic reticulum stress (ERS)-induced apoptosis serves a crucial role in the pathogenesis of myocardial ischemia/reperfusion injury (MIRI). Previous studies have confirmed that pleckstrin homology-like domain family A member 3 (PHLDA3) is an important mediator in ERS-associated apoptosis. The a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Ther Med
Main Authors: Liu, Kai, Chen, Ying, Ai, Fen, Li, Yun-Qian, Zhang, Kun, Zhang, Wei-Tong
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2021
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082641/
https://ncbi.nlm.nih.gov/pubmed/33936270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.10045
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