CYP2E1, GSTM1, and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai tuberculosis patients

Antituberculosis drug-induced liver injury (ATDILI) is the common adverse reaction of antituberculosis drugs. Glutathione S-transferases (GSTs), which are phase II metabolizing enzymes for detoxification, are recognized as potential mediators of hepatotoxicity. However, role of GSTs polymorphisms in...

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Veröffentlicht in:Heliyon
Hauptverfasser: Chanhom, Noppadol, Wattanapokayakit, Sukanya, Satproedprai, Nusara, Suvichapanich, Supharat, Mahasirimongkol, Surakameth, Chaikledkaew, Usa, Udomsinprasert, Wanvisa, Mushiroda, Taisei, Jittikoon, Jiraphun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082558/
https://ncbi.nlm.nih.gov/pubmed/33981901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e06852
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