Replication and Meta-Analyses Nominate Numerous Eosinophilic Esophagitis Risk Genes

BACKGROUND: Eosinophilic esophagitis (EoE) is an emerging, chronic, rare allergic disease associated with marked eosinophil accumulation in the esophagus. Prior genome-wide association studies (GWAS) have provided strong evidence for three genome-wide susceptibility loci. OBJECTIVE: We aimed to repl...

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Publicado no:J Allergy Clin Immunol
Main Authors: Kottyan, Leah C., Trimarchi, Michael P., Lu, Xiaoming, Caldwell, Julie M., Maddox, Avery, Parameswaran, Sreeja, Lape, Michael, D’Mello, Rahul J., Bonfield, Madeline, Ballaban, Adina, Mukkada, Vincent, Putnam, Philip E, Abonia, Pablo, Baruch, Netali Ben, Eapen, Amy A., Wen, Ting, Weirauch, Matthew T., Rothenberg, Marc E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082436/
https://ncbi.nlm.nih.gov/pubmed/33446330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.10.018
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