C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera

Systemic complement activation drives a plethora of pathological conditions, but its role in snake envenoming remains obscure. Here, we explored complement’s contribution to the physiopathogenesis of Naja annulifera envenomation. We found that N. annulifera venom promoted the generation of C3a, C4a,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Silva de França, Felipe, Villas-Boas, Isadora Maria, Cogliati, Bruno, Woodruff, Trent M., Reis, Edimara da Silva, Lambris, John D., Tambourgi, Denise V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082402/
https://ncbi.nlm.nih.gov/pubmed/33936074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.652242
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