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TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

Voluntary exercise is well known to benefit brain performance. In contrast, forced exercise induces inflammation-related stress responses and may cause psychiatric disorders. Here, we unexpectedly found that rotarod testing, a frequently applied assay for evaluating rodent motor coordination, induce...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Hung, Yun-Fen, Hsueh, Yi-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082089/
https://ncbi.nlm.nih.gov/pubmed/33981972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102384
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