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TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

Voluntary exercise is well known to benefit brain performance. In contrast, forced exercise induces inflammation-related stress responses and may cause psychiatric disorders. Here, we unexpectedly found that rotarod testing, a frequently applied assay for evaluating rodent motor coordination, induce...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:iScience
Egile Nagusiak: Hung, Yun-Fen, Hsueh, Yi-Ping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082089/
https://ncbi.nlm.nih.gov/pubmed/33981972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102384
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