The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development

Accumulating evidence indicates that breakdown of the+ protective mucosal barrier of the gut plays a role in colorectal cancer (CRC) development. Inflammation and oxidative stress in the colonic epithelium are thought to be involved in colorectal carcinogenesis and the breakdown of the integrity of...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Genua, Flavia, Raghunathan, Vedhika, Jenab, Mazda, Gallagher, William M., Hughes, David J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082020/
https://ncbi.nlm.nih.gov/pubmed/33937029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.626349
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