Inflammation Pharmacological Reaction and YMDD Mutational Patterns in Lamivudine Therapeutics Hepatitis B Virus

Background/Aims: Emergence of tyrosine-methionine-aspartate-aspartate (YMDD) motif in reverse transcriptase is a serious problem in chronic hepatitis B(CHB) patients after Lamivudine (LAM) therapy. However, the relationship between inflammation pharmacological reaction and YMDD mutational patterns o...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Liu, Hongcan, Wan, Zemin, She, Lanhui, Zhu, Yajuan, Cai, Zhiliang, Wu, Bin, Zhuang, Qizhen, Ke, Peifeng, Wu, Xinzhong, Li, Zhuo, Huang, Xianzhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081950/
https://ncbi.nlm.nih.gov/pubmed/33935748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.648170
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