PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway

BACKGROUND: Traumatic spinal cord injury (SCI) causes severe motor dysfunction and persistent central neuropathic pain (Nep), which has not yet been effectively cured. Programmed cell death ligand-1 (PD-L1) is typically produced by cancer cells and contributes to the immune-suppressive in tumor micr...

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Udgivet i:Front Immunol
Main Authors: Kong, Fanqi, Sun, Kaiqiang, Zhu, Jian, Li, Fudong, Lin, Feng, Sun, Xiaofei, Luo, Xi, Ren, Changzhen, Lu, Lantao, Zhao, ShuJie, Sun, Jingchuan, Wang, Yuan, Shi, Jiangang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081847/
https://ncbi.nlm.nih.gov/pubmed/33936116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.670646
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