Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways

Total flavonoids of Rhizoma Drynariae (TFRD) have been shown to have beneficial effects on osteoarthritis (OA) clinically, but the mechanisms have not been elucidated. In this study, we investigated the effect of TFRD on articular cartilage in an OA rat model established by the Hulth method and in S...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Chen, Guang-Yao, Chen, Jia-Qi, Liu, Xiao-Yu, Xu, Yuan, Luo, Jing, Wang, Yi-Fei, Zhou, Tong-Liang, Yan, Ze-Ran, Zhou, Li, Tao, Qing-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081598/
https://ncbi.nlm.nih.gov/pubmed/33995548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6634837
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