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Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization

The development of a universal vaccine against foot-and-mouth disease virus (FMDV) is hindered by cross-serotype antigenic diversity and by a lack of knowledge regarding neutralization of the virus in natural hosts. In this study, we isolated serotype O-specific neutralizing antibodies (NAbs) (F145...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: He, Yong, Li, Kun, Cao, Yimei, Sun, Zixian, Li, Pinghua, Bao, Huifang, Wang, Sheng, Zhu, Guoqiang, Bai, Xingwen, Sun, Pu, Liu, Xuerong, Yang, Cheng, Liu, Zaixin, Lu, Zengjun, Rao, Zihe, Lou, Zhiyong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081260/
https://ncbi.nlm.nih.gov/pubmed/33909694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009507
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