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Evogliptin, a dipeptidyl peptidase-4 inhibitor, attenuates pathological retinal angiogenesis by suppressing vascular endothelial growth factor-induced Arf6 activation

Dipeptidyl peptidase-4 (DPP-4) inhibitors are used for the treatment of type 2 diabetes mellitus (DM). Recent studies have shown that beyond their effect in lowing glucose, DPP-4 inhibitors mitigate DM-related microvascular complications, such as diabetic retinopathy. However, the mechanism by which...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Seo, Songyi, Kim, Mi-Kyung, Kim, Ryul-I, Yeo, Yeongju, Kim, Koung Li, Suh, Wonhee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080693/
https://ncbi.nlm.nih.gov/pubmed/33051573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-00512-8
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