Cancer cells undergoing epigenetic transition show short-term resistance and are transformed into cells with medium-term resistance by drug treatment

To elucidate the epigenetic mechanisms of drug resistance, epigenetically reprogrammed H460 cancer cells (R-H460) were established by the transient introduction of reprogramming factors. Then, the R-H460 cells were induced to differentiate by the withdrawal of stem cell media for various durations,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Mol Med
Prif Awduron: Poojan, Shiv, Bae, Seung-Hyun, Min, Jae-Woong, Lee, Eun Young, Song, Yura, Kim, Hee Yeon, Sim, Hye Won, Kang, Eun-Kyung, Kim, Young-Ho, Lee, Hae-Ock, Hong, Yourae, Park, Woong-Yang, Jang, Hyonchol, Hong, Kyeong-Man
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080688/
https://ncbi.nlm.nih.gov/pubmed/32661348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0464-3
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