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β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice

In patients with chronic kidney disease, skeletal muscle dysfunction is associated with mortality. Uremic sarcopenia is caused by ageing, malnutrition, and chronic inflammation, but the molecular mechanism and potential therapeutics have not been fully elucidated yet. We hypothesize that accumulated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Higashihara, Takaaki, Nishi, Hiroshi, Takemura, Koji, Watanabe, Hiroshi, Maruyama, Toru, Inagi, Reiko, Tanaka, Tetsuhiro, Nangaku, Masaomi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080640/
https://ncbi.nlm.nih.gov/pubmed/33911115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88438-7
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