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β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice

In patients with chronic kidney disease, skeletal muscle dysfunction is associated with mortality. Uremic sarcopenia is caused by ageing, malnutrition, and chronic inflammation, but the molecular mechanism and potential therapeutics have not been fully elucidated yet. We hypothesize that accumulated...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Higashihara, Takaaki, Nishi, Hiroshi, Takemura, Koji, Watanabe, Hiroshi, Maruyama, Toru, Inagi, Reiko, Tanaka, Tetsuhiro, Nangaku, Masaomi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080640/
https://ncbi.nlm.nih.gov/pubmed/33911115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88438-7
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