Modulation of α(V)β(6) integrin in osteoarthritis-related synovitis and the interaction with VTN((381–397 a.a.)) competing for TGF-β1 activation

Osteoarthritis is characterized by structural alteration of joints. Fibrosis of the synovial tissue is often detected and considered one of the main causes of joint stiffness and pain. In our earlier proteomic study, increased levels of vitronectin (VTN) fragment (amino acids 381–397) were observed...

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Publicat a:Exp Mol Med
Autors principals: Ciregia, Federica, Deroyer, Céline, Cobraiville, Gaël, Plener, Zelda, Malaise, Olivier, Gillet, Philippe, Fillet, Marianne, Malaise, Michel G., de Seny, Dominique
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080589/
https://ncbi.nlm.nih.gov/pubmed/33526813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-021-00558-2
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