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Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice

Exposure to air pollution from traffic-generated sources is known to contribute to the etiology of inflammatory diseases, including cardiovascular disease (CVD) and obesity; however, the signaling pathways involved are still under investigation. Dysregulation of the renin-angiotensin system (RAS) ca...

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Pubblicato in:Toxicol Rep
Autori principali: Phipps, Benjamin L., Suwannasual, Usa, Lucero, JoAnn, Mitchell, Nicholas A., Lund, Amie K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080412/
https://ncbi.nlm.nih.gov/pubmed/33948438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2021.04.001
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