Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma

Glioblastomas (GBMs) are the most common primary brain tumors characterized by strong invasiveness and angiogenesis. GBM cells and microenvironment secrete angiogenic factors and also express chemoattractant G protein-coupled receptors (GPCRs) to their advantage. We investigated the role of the vaso...

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Bibliografiska uppgifter
I publikationen:Front Cell Dev Biol
Huvudupphovsmän: Le Joncour, Vadim, Guichet, Pierre-Olivier, Dembélé, Kleouforo-Paul, Mutel, Alexandre, Campisi, Daniele, Perzo, Nicolas, Desrues, Laurence, Modzelewski, Romain, Couraud, Pierre-Olivier, Honnorat, Jérôme, Ferracci, François-Xavier, Marguet, Florent, Laquerrière, Annie, Vera, Pierre, Bohn, Pierre, Langlois, Olivier, Morin, Fabrice, Gandolfo, Pierrick, Castel, Hélène
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Cell and Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079989/
https://ncbi.nlm.nih.gov/pubmed/33937253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.652544
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