Colorimetric RT-LAMP SARS-CoV-2 diagnostic sensitivity relies on color interpretation and viral load

The use of RT-LAMP (reverse transcriptase—loop mediated isothermal amplification) has been considered as a promising point-of-care method to diagnose COVID-19. In this manuscript we show that the RT-LAMP reaction has a sensitivity of only 200 RNA virus copies, with a color change from pink to yellow...

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Publicado en:Sci Rep
Main Authors: Aoki, Mateus Nóbrega, de Oliveira Coelho, Bruna, Góes, Luiz Gustavo Bentim, Minoprio, Paola, Durigon, Edison Luiz, Morello, Luis Gustavo, Marchini, Fabricio Klerynton, Riediger, Irina Natassja, do Carmo Debur, Maria, Nakaya, Helder I., Blanes, Lucas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079700/
https://ncbi.nlm.nih.gov/pubmed/33907239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88506-y
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