Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease

White matter (WM) alterations have been identified as a relevant pathological feature of Huntington’s disease (HD). Increasing evidence suggests that WM changes in this disorder are due to alterations in myelin‐associated biological processes. Multi-compartmental analysis of the complex gradient-ech...

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Detalles Bibliográficos
Publicado en:Neuroimage Clin
Main Authors: Casella, Chiara, Kleban, Elena, Rosser, Anne E., Coulthard, Elizabeth, Rickards, Hugh, Fasano, Fabrizio, Metzler-Baddeley, Claudia, Jones, Derek K.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079666/
https://ncbi.nlm.nih.gov/pubmed/33865029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2021.102658
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