Periplasmic synthesis and purification of the human prolactin antagonist Δ(1-11)-G129R-hPRL

The human prolactin antagonist Δ(1-11)-G129R-hPRL is a 21.9 kDa recombinant protein with 188 amino acids that downregulates the proliferation of a variety of cells expressing prolactin receptors. Periplasmic expression of recombinant proteins in E. coli has been considered an option for obtaining a...

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Publicat a:AMB Express
Autors principals: Suzuki, Miriam F., Almeida, Larissa A., Pomin, Stephanie A., Silva, Felipe D., Freire, Renan P., Oliveira, João E., Affonso, Regina, Soares, Carlos R. J., Bartolini, Paolo
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079533/
https://ncbi.nlm.nih.gov/pubmed/33905023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-021-01209-5
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