Quantitative Proteomics Reveals that the OGT Interactome Is Remodeled in Response to Oxidative Stress

The dynamic modification of specific serine and threonine residues of intracellular proteins by O-linked N-acetyl-β-D-glucosamine (O-GlcNAc) mitigates injury and promotes cytoprotection in a variety of stress models. The O-GlcNAc transferase (OGT) and the O-GlcNAcase are the sole enzymes that add an...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Martinez, Marissa, Renuse, Santosh, Kreimer, Simion, O’Meally, Robert, Natov, Peter, Madugundu, Anil K., Nirujogi, Raja Sekhar, Tahir, Raiha, Cole, Robert, Pandey, Akhilesh, Zachara, Natasha E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079276/
https://ncbi.nlm.nih.gov/pubmed/33716169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcpro.2021.100069
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