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Characterization and Pharmacokinetic Evaluation of Oxaliplatin Long-Circulating Liposomes

The clinical efficacy of Oxaliplatin (L-OHP) is potentially limited by dose-dependent neurotoxicity and high partitioning to erythrocytes in vivo. Long-circulating liposomes could improve the pharmacokinetic profile of L-OHP and thus enhance its therapeutic efficacy and reduce its toxicity. The purp...

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Publicat a:Biomed Res Int
Autors principals: Cheraga, Nihad, Ouahab, Ammar, Shen, Yan, Huang, Ning-Ping
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079196/
https://ncbi.nlm.nih.gov/pubmed/33987441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5949804
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