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The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection

Regulation of mitochondrial structure and function is a central component of infection with viruses, including human cytomegalovirus (HCMV), as a virus means to modulate cellular metabolism and immune responses. Here, we link the activity of the mitochondrial deacetylase SIRT3 and global mitochondri...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Sheng, Xinlei, Cristea, Ileana M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078788/
https://ncbi.nlm.nih.gov/pubmed/33857259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009506
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