Germline DNMT3A mutation in familial acute myeloid leukaemia

Acute myeloid leukaemia (AML) is a heterogeneous myeloid malignancy characterized by recurrent clonal events, including mutations in epigenetically relevant genes such as DNMT3A, ASXL1, IDH1/2, and TET2. Next-generation sequencing analysis of a mother and son pair who both developed adult-onset dipl...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: DiNardo, Courtney D., Beird, Hannah C., Estecio, Marcos, Hardikar, Swanand, Takahashi, Koichi, Bannon, Sarah A., Borthakur, Gautam, Jabbour, Elias, Gumbs, Curtis, Khoury, Joseph D., Routbort, Mark, Gong, Ting, Kondo, Kimie, Kantarjian, Hagop, Garcia-Manero, Guillermo, Chen, Taiping, Futreal, P. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078744/
https://ncbi.nlm.nih.gov/pubmed/32856987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1809871
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