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MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells

Glioblastoma (GBM) is the most aggressive and lethal neoplasia of the central nervous system in adults. Based on the molecular signature genes, GBM has been classified in proneural, neural, mesenchymal and classical subtypes. The Metallophosphoesterase-domain-containing protein 2 (MPPED2) gene encod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Pellecchia, Simona, De Martino, Marco, Esposito, Francesco, Quintavalle, Cristina, Fusco, Alfredo, Pallante, Pierlorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078659/
https://ncbi.nlm.nih.gov/pubmed/33734003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2021.1901042
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