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NKX6-1 mediates cancer stem-like properties and regulates sonic hedgehog signaling in leiomyosarcoma

BACKGROUND: Leiomyosarcoma (LMS), the most common soft tissue sarcoma, exhibits heterogeneous and complex genetic karyotypes with severe chromosomal instability and rearrangement and poor prognosis. METHODS: Clinical variables associated with NKX6-1 were obtained from The Cancer Genome Atlas (TCGA)....

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Bibliografiske detaljer
Udgivet i:J Biomed Sci
Main Authors: Su, Po-Hsuan, Huang, Rui-Lan, Lai, Hung-Cheng, Chen, Lin-Yu, Weng, Yu-Chun, Wang, Chih-Chien, Wu, Chia-Chun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077933/
https://ncbi.nlm.nih.gov/pubmed/33906647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00726-6
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