P2X(3) receptor upregulation in trigeminal ganglion neurons through TNFα production in macrophages contributes to trigeminal neuropathic pain in rats

BACKGROUND: Trigeminal neuralgia is a characteristic disease that manifests as orofacial phasic or continuous severe pain triggered by innocuous orofacial stimulation; its mechanisms are not fully understood. In this study, we established a new animal model of trigeminal neuralgia and investigated t...

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Dettagli Bibliografici
Pubblicato in:J Headache Pain
Autori principali: Koizumi, Momoko, Asano, Sayaka, Furukawa, Akihiko, Hayashi, Yoshinori, Hitomi, Suzuro, Shibuta, Ikuko, Hayashi, Katsuhiko, Kato, Fusao, Iwata, Koichi, Shinoda, Masamichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Milan 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077728/
https://ncbi.nlm.nih.gov/pubmed/33902429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-021-01244-4
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