Arid1a regulates cell cycle exit of transit-amplifying cells by inhibiting the Aurka-Cdk1 axis in mouse incisor

Stem cells self-renew or give rise to transit-amplifying cells (TACs) that differentiate into specific functional cell types. The fate determination of stem cells to TACs and their transition to fully differentiated progeny is precisely regulated to maintain tissue homeostasis. Arid1a, a core compon...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Du, Jiahui, Jing, Junjun, Chen, Shuo, Yuan, Yuan, Feng, Jifan, Ho, Thach-Vu, Sehgal, Prerna, Xu, Jian, Jiang, Xinquan, Chai, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077510/
https://ncbi.nlm.nih.gov/pubmed/33766930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.198838
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