Loss‐of‐function or gain‐of‐function variations in VINCULIN (VCL) are risk factors of human neural tube defects

BACKGROUND: Neural tube defects (NTDs) are severe birth defects resulting from the failure of neural tube closure during embryogenesis. Both genetic and environmental factors contribute to the occurrence of NTDs and the heritability of NTDs is approximately 70%. As a key component of focal adhesions...

Full description

Saved in:
Bibliographic Details
Published in:Mol Genet Genomic Med
Main Authors: Wang, Yalan, Qin, Yue, Peng, Rui, Wang, Hongyan
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077129/
https://ncbi.nlm.nih.gov/pubmed/33491343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1563
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items