Baricitinib Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating the Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathway

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS) and a CD4+ T cell-mediated autoimmune disease. The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is recognized as the major mechanism that regulates the differentiation...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Dang, Chun, Lu, Yaoheng, Chen, Xingyu, Li, Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076548/
https://ncbi.nlm.nih.gov/pubmed/33927721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.650708
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