Optimized Parameters for Transducing the Locus Coeruleus Using Canine Adenovirus Type 2 (CAV2) Vector in Rats for Chemogenetic Modulation Research

INTRODUCTION: The locus coeruleus noradrenergic (LC-NA) system is studied for its role in various neurological and psychiatric disorders such as epilepsy and Major Depression Dissorder. Chemogenetics is a powerful technique for specific manipulation of the LC to investigate its functioning. Local in...

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Foilsithe in:Front Neurosci
Main Authors: Stevens, Latoya, Larsen, Lars Emil, Van Lysebettens, Wouter, Carrette, Evelien, Boon, Paul, Raedt, Robrecht, Vonck, Kristl
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076532/
https://ncbi.nlm.nih.gov/pubmed/33927593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.663337
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