Transitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study)

BACKGROUND: Oral and gut microbiomes have emerged as potential biomarkers in cancer. We characterised the oral and gut microbiomes in a prospective observational cohort of HPV+ oropharyngeal squamous cell carcinoma (OPSCC) patients and evaluated the impact of chemoradiotherapy (CRT). METHODS: Saliva...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Oliva, Marc, Schneeberger, Pierre H. H., Rey, Victor, Cho, Matthew, Taylor, Rachel, Hansen, Aaron R., Taylor, Kirsty, Hosni, Ali, Bayley, Andrew, Hope, Andrew J., Bratman, Scott V., Ringash, Jolie, Singh, Simron, Weinreb, Ilan, Perez-Ordoñez, Bayardo, Chepeha, Douglas, Waldron, John, Xu, Wei, Guttman, David, Siu, Lillian L., Coburn, Bryan, Spreafico, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076306/
https://ncbi.nlm.nih.gov/pubmed/33750907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01253-1
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