MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies

Nutritional status during gestation may lead to a phenomenon known as metabolic programming, which can be triggered by epigenetic mechanisms. The Let-7 family of microRNAs were one of the first to be discovered, and are closely related to metabolic processes. Bioinformatic analysis revealed that Prk...

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Vydáno v:Sci Rep
Hlavní autoři: Simino, Laís A. P., Panzarin, Carolina, Fontana, Marina F., de Fante, Thais, Geraldo, Murilo V., Ignácio-Souza, Letícia M., Milanski, Marciane, Torsoni, Marcio A., Ross, Michael G., Desai, Mina, Torsoni, Adriana S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076304/
https://ncbi.nlm.nih.gov/pubmed/33903707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88518-8
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