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Cycle Development in a Mini-Freeze Dryer: Evaluation of Manometric Temperature Measurement in Small-Scale Equipment

The objective of this research was to assess the applicability of manometric temperature measurement (MTM) and SMART™ for cycle development and monitoring of critical product and process parameters in a mini-freeze dryer using a small set of seven vials. Freeze drying cycles were developed using SMA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:AAPS PharmSciTech
Hauptverfasser: Wenzel, Tim, Gieseler, Margit, Abdul-Fattah, Ahmad M., Gieseler, Henning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076153/
https://ncbi.nlm.nih.gov/pubmed/33903988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-021-02014-w
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