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Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies

Programmed cell death ligand-1 (PD-L1) expression levels in patient tumor samples have proven clinical utility across various cancer types. Several independently developed PD-L1 immunohistochemical (IHC) predictive assays are commercially available. Published studies using the VENTANA PD-L1 (SP263)...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Lawson, Nicola L., Dix, Carly I., Scorer, Paul W., Stubbs, Christopher J., Wong, Edmond, Hutchinson, Liam, McCall, Eileen J., Schimpl, Marianne, DeVries, Emma, Walker, Jill, Williams, Gareth H., Hunt, James, Barker, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075905/
https://ncbi.nlm.nih.gov/pubmed/31558782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-019-0372-z
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