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Angiotensin Ⅱ通过氧化应激引起巨噬细胞AMPK/SIRT1能量信号紊乱
OBJECTIVE: To investigate the mechanism by which angiotensin Ⅱ-induced oxidative stress response inhibits AMPK/ SIRT1 signaling in RAW264.7 macrophages. METHODS: RAW264.7 cells were treated with 0.5, 1, 3, 10, or 20 μmol/L angiotensin Ⅱ for 24 h, and the changes in the expressions of AMPK, p-AMPK, a...
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| Publicat a: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
南方医科大学学报编辑部
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8075794/ https://ncbi.nlm.nih.gov/pubmed/33849829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2021.03.10 |
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