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Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology
Translation-dependent quality control pathways such as no-go decay (NGD), non-stop decay (NSD), and nonsense-mediated decay (NMD) govern protein synthesis and proteostasis by resolving non-translating ribosomes and preventing the production of potentially toxic peptides derived from faulty and aberr...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8075583/ https://ncbi.nlm.nih.gov/pubmed/33899734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66904 |
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